Biologicals have been around for decades. And for just as long, farmers have heard the same promise: that these natural products can reduce dependence on synthetic inputs while maintaining or improving yields.

But here’s the problem: most biologicals don’t deliver consistent performance or ROI.

They sound good in theory, but in the real world—with its unpredictable weather, soil variability, and tight planting windows—the one that you farm in—they rarely perform as advertised. Ask any agronomist, and you’ll hear it again and again: Biologicals just aren’t reliable.

At IMIO, we’ve spent years working to change that.

The truth is, most biologicals need a lot of things to go right in order to work.

They’re sensitive to heat and handling. Many lose effectiveness in shipping or storage, long before they reach your soil. Farmers were often told to just mix them in with their usual inputs without being warned that herbicides, fungicides, or even water quality could kill off the microbes.

And once they were in the field? The microbes still had a long list of hurdles: survive harsh field conditions, colonize plant roots, form multi-stage symbiotic relationships, all while competing with native microbes in the soil.

Some growers saw benefits. Many didn’t. What sounded great in the sales pitch often didn’t show up on the yield monitor.

That’s not a reliable tool. That’s a roll of the dice.

Enter Re-Gen: The Bulletproof Biological for Nutrient Recapture

Re-Gen was designed to take the chance out of using biologicals. We re-engineered the biological from the ground up to deliver consistent, reliable performance and ROI across crops, climates, and soil conditions.

Re-Gen is freeze-dried into a shelf-stable powder using a specialized lyophilization protocol. No refrigeration required. No viability loss in transit. 

Because Re-Gen is freeze-dried and activated on site, it delivers 100,000X more active microbes than leading competitors. Guaranteed.

In field trials spanning over 1,100 acres and multiple regions, Re-Gen has consistently delivered:

3.9% milk yield increase (from more nutritious silage)

That’s why we believe Re-Gen isn’t just a better biological. It’s a better agricultural input, period.

Re-Gen isn’t just more reliable because of what it does. It’s reliable because of how it does it.

While other biologicals depend on a complex chain of events—microbial colonization, symbiosis, perfect soil conditions—Re-Gen takes a more direct route: breaking down crop residue to unlock the nutrients already in your field.

That straightforward, mechanical action means fewer points of failure and far more consistent results.

Reliability isn’t just about biology. It’s also about manufacturing.

Each of the microbes in Re-Gen is cultured and tested individually, then blended in precise ratios to ensure consistency from batch to batch. That means the product you use this season will perform just like it did last season.

Farmers don’t have time for products that only work some of the time. You need tools that deliver a return: reliably, repeatably, regardless of what the season throws at them.

That’s a high standard. But it’s one that Re-Gen is ready to meet.

So if you’ve been burned by biologicals in the past—or you’re just tired of hoping something works—give Re-Gen a closer look. 

Want to see what Re-Gen can do in your fields? Let’s talk.

How Re-Gen Solves the Reliability Problem in Biologicals

Every year, farmers apply fertilizer to ensure their crops have the nutrients they need to thrive. And every year, a major source of those same nutrients goes untapped, right under their boots.

We're talking about crop residue and cover crops. These materials are packed with nitrogen, phosphorus, and potassium—the same nutrients you pay for in synthetic form. But if those nutrients remain locked away in tough plant material, they can’t help your next crop. That's where nutrient recapture comes in.

At IMIO, we believe it’s time to stop thinking about residue management and start thinking about nutrient recapture—an approach that turns plant “waste” into nutrient value.

Crop residues and cover crops aren't trash. They're fertilizer waiting to be released.

Let's take a look at the potential dollar value of common residue types, based on their nutrient content:

These figures combine the estimated market value of nitrogen, phosphorus, and potassium contained in the crop material. In many cases, you're looking at over $200 per acre of fertility value that's already in your field, already paid for in seed, labor, and biomass.

Farmers already know this value exists. The question is whether you can access it.

Why Nutrient Recapture Beats Residue Management

Residue management products focus on making plant residue "go away." But that's not the same as unlocking nutrients. Most of these products rely on low-activity, bacteria-only blends that fall short when it comes to breaking down lignin and cellulose—the tough stuff in stalks and stems that hold the nutrients in.

Re-Gen, IMIO's nutrient recapture product, is built to do something different: free those nutrients and return them to the soil, where your next crop can use them. These differences in product composition matter. Especially when it comes to fungi.

Fungi are nature's best decomposers. They excel at breaking down lignin and cellulose. A 2025 study in Genome Biology put it clearly: “Fungi consistently act as the dominant decomposers... Bacteria predominantly exploit fungal degradation products.”

In short: fungi unlock the value, and bacteria follow behind. If your biological only contains bacteria, you’re missing the main driver of nutrient recapture.

Re-Gen includes fungi (plus bacteria and yeast) and uses a freeze-drying process to preserve microbial activity. This gives Re-Gen a broader spectrum of biology and higher effectiveness in the field.

If you’re spending $100–$200 per acre on synthetic fertilizer—and leaving another $200 per acre of organic fertility untouched—you’re missing a major opportunity.

Nutrient recapture closes that gap. It helps you:

Speed residue breakdown for cleaner seedbeds

Restore microbial balance with a broader biological profile

Farmers who’ve adopted Re-Gen report not only faster decomposition and cleaner fields, but also peace of mind knowing they’re getting more from what they’ve already invested in. Read our case studies to learn more.

Cover crops and residues are full of nutrients your crops need.

Nutrient recapture means recognizing and reclaiming that value. It’s not just good biology. It’s good business.

If you’re ready to stop leaving nutrient value on the table, let’s talk.

Nutrient Recapture: Unlocking the Hidden Value in Your Fields

From GPS-guided tractors to soil sensors and satellite imagery, modern-day technology has driven farming forward in countless ways. 

But, as much as tech helps, it can also get in the way—locking up your equipment, increasing your maintenance costs, or complicating what you already know to be true.

At IMIO, we believe tech works best when it fades to the background. When it doesn't stand in the way of farmers doing what they know is best. 

That’s the philosophy behind Re-Gen. It’s a practical tool that quickly, reliably upgrades your existing fertility program without requiring complex changes.

We think of Re-Gen as common-sense biotech. It’s designed for a single purpose: to help you get more from what’s already in your fields.

That means pulling nitrogen, phosphorus, and potassium back out of the plant material you’ve already invested in—corn stalks, romaine residue, cover crops—and putting it to work for your next crop.

With a simple mix-and-spray application, Re-Gen delivers:

20+ bushel yield increases in corn trials

Nutrient Recapture, Not Residue Management

Most residue products aim to make crop waste “go away.” But let’s call that what it is: wasteful.

There’s real nutrient value locked in every stem and stalk. If you’re not unlocking it, you’re leaving money in the field. 

Re-Gen wasn’t made for test plots or theoretical models. It was built for the real-world pressures of farming—tight windows, unpredictable weather, and the need to make every input count.

That’s why everything about Re-Gen is designed for simplicity and reliability:

Shelf-stable storage: Re-Gen ships as a freeze-dried powder with no special storage requirements. Just toss it on the shelf and pull it down when you’re ready.

Easy mixing: Add water, wait a few hours, and you’re good to go. You don't need special tanks, agitators, or complicated protocols. Farmers use Re-Gen in their existing spray equipment with minimal adjustment.

Flexible application: Re-Gen fits seamlessly into your existing workflow. Whether you’re running 10-gallon ground rigs or flying low with a drone, Re-Gen applies clean and stays active. It works with most water sources.

No system overhaul required: Re-Gen isn’t another “stack” or specialty system. It’s a plug-and-play upgrade. Spray it on your residue, and let the biology do the work.

Re-Gen is a practical upgrade to your fertility program. One that gives you more from what you already have. 

So if you’re looking for one piece of tech that actually keeps things simple, take a closer look at Re-Gen.

Because the best tech delivers results without getting in your way.

Want to learn more about Re-Gen? We'd love to start a conversation.

Common Sense Over Complexity

High Return, Low Fuss

Nutrient Recapture, Not Residue Management

Built for Farms, Not Labs

The Bottom Line

More blog posts

How Re-Gen Solves the Reliability Problem in Biologicals

Nutrient Recapture: Unlocking the Hidden Value in Your Fields